Divisions
Cipla Medpro Manufacturing (CMM)
Bringing world class, flexible, contract manufacturing solutions
to South Africa.
Situated in Durban, Cipla Medpro Manufacturing (Pty) Ltd is one
of South Africa's largest pharmaceutical manufacturing plants,
approved by the SA Medicines Control Council (MCC), and headed by a
strong, experienced management team.
CMM is fully equipped to offer local and multinational
pharmaceutical companies world class, high volume manufacturing
solutions in line with MCC cGMP (current Good Manufacturing
Practice) and PIC/S standards.
CMM is also one of only two facilities in South Africa offering
manufacturing capability for effervescent formulations.
Through its close association with Cipla India, experts in
pharmaceutical manufacturing to globally accredited standards for
over 75 years, CMM benefits from their manufacturing expertise and
customers are assured the benefit of our competitive advantage and
strong buying power when sourcing raw materials.
Unique design and capabilities, from
start to finish.
The facility is uniquely designed in that there is physical
segregation between stores, primary and secondary processing areas.
This minimises the risk of contamination and ensures material flow
is uni-directional. All incoming materials are received in
accordance to cGMP principles and are housed in dedicated
warehouses i.e. primary, secondary etc. Warehouses, including the
finished goods store, are temperature and humidity controlled in
accordance with required material storage conditions.
CMM currently
offers:
- Four dispensaries each with uni-directional airflow units
designed to protect the operator and product from exposure during
dispensing activities;
- Three granulation suites equipped with a range of granulators
and driers;
- One blending room for mixing powders and granules;
- Compression and encapsulation departments equipped with state
of the art machines;
- Coating suites with state of the art coaters. Two high-tech
coaters are capable of coating large batch sizes in optimum time.
Coating capabilities include solvent, aqueous and sugar
coating.
- A fully validated, computerised maintenance system is in place
to ensure that all preventive maintenance and calibrations are done
in a systematic, electronic and optimal format, thus significantly
reducing potential for human error. This capability is unique in
the local pharmaceutical manufacturing environment.
- New stability chambers
Further improvements undertaken
are:
- A major upgrade of the Quality Control Laboratory and the
Microbiology Laboratory
- Modern high tech equipment for the prodution areas
Dedicated Tech Transfer
team:
As a contract manufacturer, CMM recognises the importance of
having a skilled, experienced and efficient team involved in
the introduction of new products into the facility. As such,
a dedicated technology transfer team comprising technology transfer
pharmacists, laboratory personnel and a project co-ordinator
facilitate the smooth introduction of new products into the
facility, in accordance with cGMP requirements.
Experienced management and full systems support ensures
peace of mind:
CMM's 300-strong staff complement is headed by a strong management
team experienced in international manufacturing practices. A full
engineering support team is on site to maintain the state of the
art equipment and ensure continuous machine operation and minimize
downtimes through an extensive preventive maintenance program.
A highly skilled team of qualified professionals across all
areas and departments ensure that quality assurance, quality
systems, technology transfer and manufacturing processes are
maintained at international standards.
Capabilities:
The following range of products can currently be manufactured:
- Tablets (un-coated or film/sugar coated)
- Capsules
- Powders
- Effervescent powders and granules
Processes:
- Dry blending/ Direct compression
- Wet granulation aqueous /non-aqueous (vertical granulators,
planetary mixers , FBE's)
- Conventional tray drying
- Fluid-bed drying
- Tabletting
- Encapsulation
- Aqueous or solvent based film coating
- Effervescent manufacturing and packing
Packaging:
- Blister (PVC or PVC/PVDC; ALU/ALU)
- Sachets (granules/powder)
- Glass bottles (granules/powder)
- Bulk packaging
- Tablet container packaging
- Effervescent packaging
- Patient ready zip packs
Animal Healthcare
Cipla Nutrition
www.ciplanutrition.com